How every lot is tested

BioMethod Labs does not perform in-house testing. Every lot is sent to an independent third-party analytical laboratory before release. Reports are published in full, unedited.

HPLC

High-performance liquid chromatography

HPLC separates the compound from any synthesis byproducts, truncated sequences, or degradation products. The resulting chromatogram quantifies purity as a percentage of total peak area. BioMethod Labs releases no lot below 99.0% purity by HPLC.

MS

Mass spectrometry

Mass spectrometry confirms molecular identity by measuring the mass-to-charge ratio of the compound. The observed molecular weight is compared against the theoretical weight of the target sequence. A lot that does not match the expected mass is rejected regardless of its purity result.

ICP-MS

Heavy metals screening

Inductively coupled plasma mass spectrometry screens for lead, arsenic, cadmium, and mercury contamination introduced during synthesis or handling. Results are reported in parts per million against USP limits.

Lead (Pb)< 0.1 ppm · pass
Arsenic (As)< 0.1 ppm · pass
Cadmium (Cd)< 0.1 ppm · pass
Mercury (Hg)< 0.1 ppm · pass

LAL

Bacterial endotoxin testing

Limulus amebocyte lysate assay detects bacterial endotoxin contamination. Reported in endotoxin units per milligram.

MethodGel clot LAL
Result< 0.05 EU/mg
Specification≤ 1.0 EU/mg
DeterminationPass

Laboratory partners

Janoshik Analytical

Independent analytical laboratory with no ownership, financial, or operational relationship to BioMethod Labs. Reports are issued directly by the laboratory and published without modification.

Colmaric Analyticals

Independent analytical laboratory with no ownership, financial, or operational relationship to BioMethod Labs. Reports are issued directly by the laboratory and published without modification.